An affordable price is probably the major benefit persuading people to buy drugs at www.americanbestpills.com. The cost of medications in Canadian drugstores is considerably lower than anywhere else simply because the medications here are oriented on international customers. In many cases, you will be able to cut your costs to a great extent and probably even save up a big fortune on your prescription drugs. What's more, pharmacies of Canada offer free-of-charge shipping, which is a convenient addition to all other benefits on offer. Cheap price is especially appealing to those users who are tight on a budget
Service Quality and Reputation Although some believe that buying online is buying a pig in the poke, it is not. Canadian online pharmacies are excellent sources of information and are open for discussions. There one can read tons of users' feedback, where they share their experience of using a particular pharmacy, say what they like or do not like about the drugs and/or service. Reputable online pharmacy canadianrxon.com take this feedback into consideration and rely on it as a kind of expert advice, which helps them constantly improve they service and ensure that their clients buy safe and effective drugs. Last, but not least is their striving to attract professional doctors. As a result, users can directly contact a qualified doctor and ask whatever questions they have about a particular drug. Most likely, a doctor will ask several questions about the condition, for which the drug is going to be used. Based on this information, he or she will advise to use or not to use this medication.

Largest Dark Web Hub for Illicit Drugs, Firearms, Malware Shutdown

Largest Dark Web Marketplace for Illicit Drugs, Firearms, Malware and More Shut Down

The largest criminal marketplace on the dark web for the illicit trade of drugs, firearms, computer hacking tools and more was shut down Thursday, the US Department of Justice (DOJ) announced.

The online marketplace, called AlphaBay, operated for more than two years, allowing buyers and sellers to anonymously exchange illegal goods and services like drugs, toxic chemicals, stolen and fraudulent identification documents and malware.

SilkRoad SeizureAlert placed on the Silk Road dark web criminal marketplace’s homepage after its seizure in 2013 (Photo: FBI, Public Domain Mark 1.0)

AlphaBay was hosted on the dark web, a hidden part of the internet that users require special software to access. One of the most common ways to access the dark web is by using a browser called Tor, which prevents network surveillance and essentially renders a user anonymous online.

Financial transactions between users on AlphaBay were conducted using cryptocurrencies, namely Bitcoin, Monero and Ethereum, according to the DOJ. Authorities believe the site was used to launder hundreds of millions of dollars from such illegal transactions.

AlphaBay was also linked to multiple overdose deaths in the US as a “major source” of fentanyl and heroin, The Independent reported.

The investigations that led to Thursday’s seizure of AlphaBay and Hansa, another major criminal market on the dark web, were led by the Federal Bureau of Investigation (FBI), the US Drug Enforcement Agency and the Dutch National Police, according to Europol, which also supported the operations.

Law enforcement agencies in Thailand, Lithuania, Canada, the UK and France also cooperated in the seizure of AlphaBay and Hansa’s digital infrastructure.

“Transnational organized crime poses a serious threat to our national and economic security,” said FBI Acting Director Andrew McCabe.

“Whether they operate in broad daylight or on the dark net, we will never stop working to find and stop these criminal syndicates.”

Authorities were able to take AlphaBay down in early July when they took the site’s alleged founder Alexandre Cazes into custody, The New York Times reported.

Cazes, 25, was a Canadian citizen living in Bangkok, Thailand. A few days after being arrested, on July 12, Cazes apparently committed suicide.

He was found to have possessed millions of dollars in cryptocurrency and luxury assets around the world, including expensive vehicles, residences and a hotel in Thailand.

At the time of its takedown, AlphaBay hosted more than 250,000 listings for illegal drugs and chemicals and more than 100,000 listings for stolen or fake documents, counterfeit goods, firearms and other illicit goods and services.

By comparison, the marketplace’s scope dwarfed the former largest illegal dark web exchange called the Silk Road, which was taken down in 2013 and had about 14,000 listings.

Europol Executive Director Rob Wainwright called AlphaBay’s demise a “massive blow to the underground criminal economy.”

However, the authorities’ fight against dark web markets is likely to continue.

In the wake of AlphaBay and Hansa’s seizure, NBC News reported a spike in traffic to a former competitor of the two marketplaces called DreamMarket, which might now enjoy a corner on the illegal market.

***

The U.S. Attorney’s Office for the Eastern District of California filed a civil forfeiture complaint against Alexandre Cazes and his wife’s assets located throughout the world, including in Thailand, Cyprus, Lichtenstein, and Antigua & Barbuda. Cazes and his wife amassed numerous high value assets, including luxury vehicles, residences and a hotel in Thailand. Cazes also possessed millions of dollars in cryptocurrency, which has been seized by the FBI and the Drug Enforcement Administration (DEA).

According to publicly available information on AlphaBay prior to its takedown, one AlphaBay staff member claimed that it serviced over 200,000 users and 40,000 vendors.  Around the time of takedown, there were over 250,000 listings for illegal drugs and toxic chemicals on AlphaBay, and over 100,000 listings for stolen and fraudulent identification documents and access devices, counterfeit goods, malware and other computer hacking tools, firearms and fraudulent services. Comparatively, the Silk Road dark web marketplace, which was seized by law enforcement in November 2013, had reportedly approximately 14,000 listings for illicit goods and services at the time of seizure and was the largest dark web marketplace at the time.

“This is likely one of the most important criminal investigations of the year – taking down the largest dark net marketplace in history,” said Attorney General Jeff Sessions. “Make no mistake, the forces of law and justice face a new challenge from the criminals and transnational criminal organizations who think they can commit their crimes with impunity using the dark net.  The dark net is not a place to hide. The Department will continue to find, arrest, prosecute, convict, and incarcerate criminals, drug traffickers and their enablers wherever they are. We will use every tool we have to stop criminals from exploiting vulnerable people and sending so many Americans to an early grave. I believe that because of this operation, the American people are safer – safer from the threat of identity fraud and malware, and safer from deadly drugs.”

“Transnational organized crime poses a serious threat to our national and economic security,” said Acting Director Andrew McCabe of the FBI. “Whether they operate in broad daylight or on the dark net, we will never stop working to find and stop these criminal syndicates.  We want to thank our international partners and those at the Department of Justice, the DEA and the IRS-CI for their hard work in demonstrating what we can do when we stand together.” More here.

Abuse of the Civil Asset Forfeiture Law

Related reading: The Myth of Judicial Activism

The Supreme Court struck down less than 1% of the federal laws passed over a 50-year period.

*** Questions must be asked why is the Justice Department re-applying this program and to what end?

Criminal forfeiture is an action brought as a part of the criminal prosecution of a defendant. It is an in personam (against the person) action and requires that the government indict (charge) the property used or derived from the crime along with the defendant. If the jury finds the property forfeitable, the court issues an order of forfeiture.

For forfeitures pursuant to the Controlled Substances Act (CSA), Racketeer Influenced and Corrupt Organizations (RICO), as well as money laundering and obscenity statutes, there is an ancillary hearing for third parties to assert their interest in the property. Once the interests of third parties are addressed, the court issues a final forfeiture order.

Civil judicial forfeiture is an in rem (against the property) action brought in court against the property. The property is the defendant and no criminal charge against the owner is necessary.

Administrative forfeiture is an in rem action that permits the federal seizing agency to forfeit the property without judicial involvement. The authority for a seizing agency to start an administrative forfeiture action is found in the Tariff Act of 1930, 19 U.S.C. § 1607. Property that can be administratively forfeited is: merchandise the importation of which is prohibited; a conveyance used to import, transport, or store a controlled substance; a monetary instrument; or other property that does not exceed $500,000 in value.

Source: A Guide to Equitable Sharing of Federally Forfeited Property for State and Local Law Enforcement Agencies, U.S. Department of Justice, March 1994.

Participants And Roles

The Justice Asset Forfeiture Program includes activity by DOJ components and several components outside the Department. Each component plays an important role in the Program.

Department of Justice Components

Money Laundering and Asset Recovery Section (MLARS) of the Criminal Division holds the responsibility of coordination, direction, and general oversight of the Program. AFMLS handles civil and criminal litigation, provides legal support to the U.S. Attorneys’ Offices, establishes policy and procedure, coordinates multi-district asset seizures, administers equitable sharing of assets, acts on petitions for remission, coordinates international forfeiture and sharing and develops training seminars for all levels of government.

Bureau of Alcohol, Tobacco, Firearms and Explosives (ATF) enforces the federal laws and regulations relating to alcohol, tobacco, firearms, explosives and arson by working directly and in cooperation with other federal, state and local law enforcement agencies. ATF has the authority to seize and forfeit firearms, ammunition, explosives, alcohol, tobacco, currency, conveyances and certain real property involved in violation of law.

Drug Enforcement Administration (DEA) implements major investigative strategies against drug networks and cartels. Enforcement operations have resulted in significant seizure and forfeiture activity. A significant portion of DEA cases are adopted from state and local law enforcement agencies.

Federal Bureau of Investigation The FBI investigates a broad range of criminal violations, integrating the use of asset forfeiture into its overall strategy to eliminate targeted criminal enterprises. The FBI has successfully used asset forfeiture in White Collar Crime, Organized Crime, Drug, Violent Crime and Terrorism investigations. See the FBI Investigative Programs Asset Forfeiture Home Page for more information.

United States Marshals Service as the primary custodian of seized property for the Program. USMS manages and disposes of the majority of the property seized for forfeiture. See their Seized Asset Information page and their National Sellers List for more information.

United States Attorneys’ Offices (USAOs) are responsible for the prosecution of both criminal and civil actions against property used or acquired during illegal activity.

Asset Forfeiture Management Staff (AFMS): Has responsibility for management of the Assets Forfeiture Fund, the Consolidated Asset Tracking System (CATS), program-wide contracts, oversight of program internal controls and property management, interpretation of the Assets Forfeiture Fund statute, approval of unusual Fund uses, and legislative liaison on matters affecting the financial integrity of the Program.

Components Outside the Department of Justice

There are several organizations outside the Department of Justice who participate in the DOJ Asset Forfeiture Program. This list may change as additional agencies and offices become part of the DOJ program. These agencies participate in Judicial forfeitures only.

United States Postal Inspection Service (USPIS) makes seizures under their authority to discourage profit-motivated crimes such as mail fraud, money laundering and drug trafficking using the mail.

Food and Drug Administration FDA’s Office of Criminal Investigations has made seizures involving health care fraud schemes, counterfeit pharmaceuticals, illegal distribution of adulterated foods, and product tampering.

United States Department of Agriculture, Office of the Inspector General USDA’s Office of Inspector General’s (OIG) mission is to promote effectiveness and integrity in the delivery of USDA agricultural programs. Forfeiture is integrated as an important law enforcement tool in combating criminal activity affecting USDA programs.

Department of State, Bureau of Diplomatic Security The Bureau of Diplomatic Security investigates passport and visa fraud and integrates asset forfeiture into our strategy to target the profits made by vendors who provide fraudulent documentation or others who utilize fraudulent visas and/or passports to further their criminal enterprises.

Defense Criminal Investigative Service (DCIS) is the criminal investigative arm of the Inspector General of the Department of Defense. The mission of DCIS is to protect America’s War fighters by conducting investigations and forfeitures in support of crucial National Defense priorities that include homeland security/terrorism, product substitution, contract fraud, public corruption, computer crimes, and illegal technology transfers. ”

The Comprehensive Crime Control Act of 1984 established the Department of Justice Assets Forfeiture Fund to receive the proceeds of forfeiture and to pay the costs associated with such forfeitures, including the costs of managing and disposing of property, satisfying valid liens, mortgages, and other innocent owner claims, and costs associated with accomplishing the legal forfeiture of the property.

The Attorney General is authorized to use the Assets Forfeiture Fund to pay any necessary expenses associated with forfeiture operations such as property seizure, detention, management, forfeiture, and disposal. The Fund may also be used to finance certain general investigative expenses. These authorized uses are enumerated in 28 U.S.C. §524(c). Read more here.

Hezbollah Terror Cells in Lebanon and Latin America

Kuwait expels Iranian diplomats over ‘terror’ cell: United Nations (United States) (AFP) – US Ambassador Nikki Haley on Wednesday accused Lebanon’s Hezbollah of amassing weapons and said the world must turn its attention to the actions of the powerful paramilitary organization.

  kataeb

Anyone ever ask or investigate the Hezbollah weapons inventory in Latin America?

 

No Latin American Country Has Branded Hezbollah a Terror Group Despite Ties to Major Attacks

WASHINGTON, D.C.—Latin American countries have failed to register Iranian proxy Hezbollah as a terrorist organization despite the threat it poses to the region, a Peruvian official revealed during a discussion on Capitol Hill.

The Shiite group is involved in various illicit activities in Latin America to generate money that some experts believe is used to fund terrorist activities in the Middle East.

During a discussion Wednesday on Capitol Hill hosted by the Center for a Secure Free Society (SFS), Moises Vega de la Cruz, a public prosecutor for the Peruvian government specializing in terrorism cases, revealed that “in Latin America, Hezbollah is not recognized as a terrorist organization.”

“I think Hezbollah is a threat to Latin America. Hezbollah is a terrorist organization that is advancing not only in Peru but in other Latin American countries as well,” he told Breitbart News.

Joseph Humire, an expert on Iranian activity in the Western Hemisphere and executive director of SFS, noted that no Latin American country has registered Hezbollah as a terrorist organization.

The United States and the European Union have deemed Lebanon’s Shiite group Hezbollah as a terrorist organization.

In the United States, Hezbollah’s main supporter Iran has been officially labeled a state sponsor of terror.

Peru recently adjudicated a case involving an alleged Hezbollah operative accused of explosives-related crimes in 2014. The individual avoided prosecution, but De La Cruz has appealed the decision.

“Most Latin Americans don’t view Islamist terrorism as a significant threat in their region and little public pressure has been placed on the establishment, reform, or improvement of weak or non-existent anti-terrorism laws across the region,” SFS pointed out in a statement. “Consequently, the Islamic State [ISIS/ISIL], Hezbollah, and other Jihadist networks and sympathizers are spreading throughout South America with impunity.”

The U.S. government has acknowledged the presence of both Shiite Hezbollah and Sunni ISIS in Latin America.

De la Cruz noted that Hezbollah maintains a presence in Peru, where it is reportedly converting people and trying to get involved politically.

The Peruvian Latina news agency reported last year that the Shiite group has registered as an official political party in Peru’s Abancay province, home to the largest concentration the country’s small Muslim community.

Hezbollah has established itself as an official political party in its main base of Lebanon.

Argentinian authorities have linked Hezbollah to fatal attacks against the South American country’s Jewish community, including the 1994 bombing of the Argentine-Israeli Mutual Association (AMIA)—the deadliest terrorist attack in the Western Hemisphere before September 11, 2001.

The U.S. military and the Department of State have expressed concern about the group’s presence in Latin America.

According to the U.S. State Department, Venezuela has provided a “permissive environment” that has allowed Hezbollah to thrive in the region.

Last year Michael Braun, a former DEA operations chief, told American lawmakers that Hezbollah is generating hundreds of millions from a “cocaine money laundering scheme” in Latin America that “provides a never-ending source of funding” for its terrorist operations in Syria and elsewhere.

Hezbollah is fighting on behalf of Iran on the side of the Russian-backed Syrian dictator Bashar al-Assad.

In an annual report to Congress issued earlier this year, U.S. Southern Command (SOUTHCOM) noted that “Hezbollah members, facilitators, and supporters engage in licit and illicit activities in support of the organization, moving weapons, cash, and other contraband to raise funds and build Hezbollah’s infrastructure in the region.”

SOUTHCOM is charged with overseeing American military activity in most of Latin America.

The group is believed to be operating throughout the Western Hemisphere.

Iran ‘foremost state sponsor of terrorism in 2016’: US state department

The department’s annual report on global terrorism accused the Iranian Revolutionary Guard’s Quds Force — which is responsible for operations outside the country — along with Iranian partners, allies, and proxies, of ‘playing a destabilising role in military conflicts in Iraq, Syria, and Yemen’

Iran was the “foremost state sponsor of terrorism in 2016”, the US state department said on Wednesday in its annual report on terrorism worldwide.

The 2016 Country Reports on Terrorism — the first released by the state department since US president Donald Trump assumed office — also highlighted Hizbollah’s increasing reach in Syria, Iraq and Yemen and an increase in “its long-term attack capabilities”.

Although the report said there had been a 9 per cent drop in global terror attacks last year from 2015, as well as a 13 per cent drop in terror-related fatalities, it stressed that “the Islamic State of Iraq and Syria (ISIS) remained the most potent terrorist threat to global security” in 2016.

Al Qaeda and its regional affiliates also “remained a threat to the US homeland and our interests abroad despite counter-terrorism pressure by US partners”, the report said.

On Iranian sponsorship of terrorism, the report accused the Revolutionary Guard’s Quds Force — which is responsible for operations outside the country — along with Iranian partners, allies, and proxies, of “playing a destabilising role in military conflicts in Iraq, Syria, and Yemen”. It also said “Iran continued to recruit fighters from across the region to join Iranian-affiliated Shia militia forces engaged in conflicts in Syria and Iraq, and has even offered a path to citizenship for those who heed this call”.

The 2016 report put more emphasis on the threat from Hizbollah than in previous years. It described the Lebanese political party and militia as “playing a major role in supporting the Syria government’s efforts to maintain control and territory, and providing training and a range of other support for Iranian-aligned fighters” in these conflict zones.

The state department said “there are reportedly about 7,000 Hizbollah fighters in Syria”, though it also highlighted that the group had lost “several senior military commanders and hundreds of fighters” in fighting there last year.

The report also highlighted Hizbollah’s continued efforts to “develop its long-term attack capabilities and infrastructure around the world”.

Justin Siberell, the state department’s acting coordinator for counter-terrorism, told The National on Wednesday that “Hizbollah maintains a sophisticated operation with [a] broad network group around the world”.

Mr Siberllel said it was unclear, however, if the Syrian conflict had boosted Hizbollah’s standing. On the one hand, the group had gained military expertise in Syria, he said, while on the other, it had suffered large number of casualties.

“It’s a mixed picture,” he said.

On Bahrain, the report said that “during 2016 the Bahraini government continued to make gains in detecting, neutralising, and containing terrorist threats from violent Shia militants and ISIS sympathisers”. It also referenced improved counter-terror co-operation with the UAE, Egypt, Saudi Arabia and other Arab countries.

The report voiced concerns over Al Qaeda exploiting the ongoing war in Yemen to make gains. It said that “despite leadership losses, Al Qaeda in the Arabian Peninsula (AQAP) remained a significant threat to Yemen, the region, and the United States, as ongoing conflict in Yemen hindered US efforts to counter the group”. It was a similar situation with Al Qaeda’s former affiliate in Syria, the report said.

“Al Nusra Front continued to exploit ongoing armed conflict to maintain a territorial safe haven in select parts of northwestern Syria,” the report said, referring to the group that now calls itself Jabhat Fatah Al Sham.

When it came to the Emirates, the report said that in 2016 “the UAE government maintained a robust counter-terrorism and countering violent extremism (CVE) partnership with the United States through its collaboration with US law enforcement; support of the Global Coalition to Defeat ISIS; and counter‑messaging initiatives, such as the Sawab and Hedayah Centers.”

The report made reference to the UAE’s deployment of forces to Yemen “to counter the spread of AQAP and ISIS” there, highlighting that, “along with its Yemeni partners, the UAE military successfully ejected AQAP from the port city of Mukalla in April — depriving AQAP from millions [of dollars] in monthly income — and from the coastal towns of Balhaf and Bir Ali in December”.

The report also highlighted wins for UAE border security.

“UAE government security apparatus continued monitoring suspected terrorists in the UAE, and successfully foiled terrorist attacks within its borders,” it said, adding: “UAE customs, police, and other security agencies improved border security and worked together with financial authorities to counter terrorist finance.”

Opioid Crisis Then and Now

The Opioid Crisis Is Dire. Why We Need a National Conversation About It Separate From Obamacare.

Let’s be honest—the opioid crisis in America is huge, it is severe, and it is devastating. But this partisan-fought legislation just isn’t the place to put that funding. And it would likely do little to help stem and reverse the opioid crisis.

First, it’s not as though funding for opioid treatment and recovery has been absent from the federal budget. As recently as last month, Sen. Susan Collins, R-Maine, was touting signed legislation that spent more than $1 billion to fund recovery programs.

This money was authorized separately from the debate over Obamacare in two pieces of legislation known as the Comprehensive Addiction and Recovery Act and the 21st Century Cures Act.

We know that prevention programs have worked in the past, whether they pertain to forest fires or drunk driving or, for that matter, the massive reduction in drug use we witnessed in the late 1980s and early 1990s.

Such a prevention program for the opioid crisis must start with leadership from the White House in leading these conversations and highlighting the devastation of substance abuse initiation.

It requires detailing what is driving the opioid epidemic—namely, illegal fentanyl, heroin, and other illegal drug use and diversion. It requires more law enforcement—from border and customs policies and cracking down on cartels to international initiatives. And it requires messaging to our youth. More here.

Socrata

This Isn’t the First U.S. Opiate-Addiction Crisis

Doctors overprescribed painkillers in the 19th century. Eventually, they stopped.

Problem and solution. Source: Museum of Science and Industry, Chicago/Getty Images

Bloomberg: The U.S. is in the throes of an “unprecedented opioid epidemic,” reports the Centers for Disease Control. The crisis has spurred calls for action to halt the rising death toll, which has devastated many rural communities.

It’s true that there’s an opioid epidemic, a public health disaster. It’s not true that it’s unprecedented. A remarkably similar epidemic beset the U.S. some 150 years ago. The story of that earlier catastrophe offers some sobering lessons as to how to address the problem.

Opioids are a broad class of drugs that relieve pain by acting directly on the central nervous system. They include substances such as morphine and its close cousin, heroin, both derived from the opium poppy. There are also synthetic versions, such as fentanyl, and medications that are derived from a mix of natural and synthetic sources, such as oxycodone.

Opioid addiction can take many forms, but the current crisis began with the use and abuse of legal painkillers in the 1990s, and has since metastasized into a larger epidemic, with heroin playing an especially outsized role.

All of this is depressingly familiar. The first great U.S. opiate-addiction epidemic began much the same way, with medications handed out by well-meaning doctors who embraced a wondrous new class of drugs as the answer to a wide range of aches and pains.

The pharmacologist Nathaniel Chapman, writing in 1817, held up opium as the most useful drug in the physician’s arsenal, arguing that there was “scarcely one morbid affection or disordered condition” that would fail to respond to its wonder-working powers. That same year, chemists devised a process for isolating a key alkaloid compound from raw opium: morphine.

Though there’s some evidence that opiate dependency had become a problem as early as the 1840s, it wasn’t until the 1860s and 1870s that addiction became a widespread phenomenon. The key, according to historian David Courtwright, was the widespread adoption of the hypodermic needle in the 1870s.

Prior to this innovation, physicians administered opiates orally. During the Civil War, for example, doctors on the Union side administered 10 million opium pills and nearly three million ounces of opium powders and tinctures. Though some soldiers undoubtedly became junkies in the process, oral administration had all manner of unpleasant gastric side effects, limiting the appeal to potential addicts.

Hypodermic needles by contrast, delivered morphine directly into a patient’s veins with no side effects, yielding immediate results. As Courtwright notes: “For the first time in the entire history of medicine near-instantaneous, symptomatic relief for a wide range of diseases was possible. A syringe of morphine was, in a very real sense, a magic wand.”

An enthusiastic medical profession began injecting morphine on a vast scale for all manner of aches and pains, much the way that a more recent generation of doctors began prescribing Oxycontin and other legal drugs in a reaction against widespread undertreatment of pain. Wounded veterans became addicts, but so, too, did people suffering from arthritis. Women also became addicts en masse, thanks to the practice of treating menstrual cramps – or for that matter, any female complaint of pain – with injections of morphine.

Skeptics in the medical profession warned about the dangers of administering too much morphine. Yet these warnings generally fell on deaf ears. Some of the problem lay with the doctors themselves. One well-regarded doctor put it this way: “Opium is often the lazy physician’s remedy.”

But distance played a role, too. Doctors traveling dirt roads on horseback couldn’t always follow up with patients in pain, and so they left their charges with vials of morphine. Well-meaning doctors who might otherwise resist administering morphine also faced pressure from patients and families to do so. If they refused, it was easy to find a doctor who would comply.

In the end, though, the medical profession largely solved the problem on its own. As awareness of physicians’ role in fostering addiction spread, medical schools taught aspiring doctors to avoid prescribing morphine except under carefully controlled circumstances. The growing availability of milder analgesics – salicylates like aspirin – made the job easier, offering a less powerful, but far safer, alternative to morphine.

While the younger generation of doctors stigmatized morphine, the problem was increasingly linked to older, poorly trained doctors who had come of age in an era when the hypodermic needle was touted as a cure-all. A study in 1919, for example, found that 90 percent of opiate prescriptions in Pennsylvania came from only a third of the state’s doctors, most of whom were over 50 years old.

As the medical profession started to police its ranks, shaming those who enabled addiction, the epidemic began to burn itself out. “Old addicts died off faster than new ones were created,” writes Courtwright. The smaller group of addicts who became the face of opiate addition tended to be poorer “pleasure users” who picked up the habit in the criminal underworld.

Today’s opioid epidemic is similar to the one that came and went over a century ago. While there is plenty of room for government assistance in funding treatment for addicts, never mind regulation of drugs, history suggests that the medical profession will ultimately play the most important role.

There are some promising signs. The number of opioid prescriptions written by doctors has dropped by small amounts over the past few years, though some of the evidence suggests that the decline has more to do with patients anxious about the potential for addiction.

Still, it took decades during the 19th century for doctors to shy away from injecting patients with morphine for the slightest complaint. It may take just as long before doctors kick the habit of prescribing powerful pain pills.

The Dark-World with U-47700 and Bitcoin

Congress should sanction China operations due to synthetic opioid production and should also list all variants of synthetic opioids as weapons of mass destruction under the chemical and biological weapons convention. DEA now has offices in China to work with officials there and investigation trafficking patterns.

The United States consumes 85% of all the world’s natural and synthetic opiates, which in 2015 factored in 33,091 U.S. deaths, up more than 4000 from the previous year, according to the U.S. Centers for Disease Control and Prevention. Opioid overdoses have quadrupled since 1999. When average U.S. life expectancies for men and women edged downward last year, for the first time in decades, many health professionals blamed opiate abuse.

The opium poppy is no longer the starting point for many of the opiates on the street. The new compounds, often sold mixed with heroin, originate in illicit labs in China. “For the cartels, why wait for a field of poppies to grow and harvest if you can get your hands on the precursor chemicals and cook a batch of fentanyl in a lab?” says Tim Reagan, resident agent in charge of the U.S. Drug Enforcement Administration’s (DEA’s) Cincinnati office.

In late 2015, the drug agency persuaded its Chinese counterpart to add 116 synthetic drugs to its list of controlled substances; fentanyl and several analogs were included. In response, underground Chinese labs began tweaking the fentanyl molecule, which is easy to alter for anyone with basic knowledge of chemistry and lab tools. By adding chemical groups, unscrupulous chemists have created new, unregulated variants, some of them even more potent than the original.

Hoping to stem the tide of synthetic opiates, DEA has taken the fight to China, as prolific a maker of illicit drugs as it is of legitimate chemicals. According to a U.S.-China Economic and Security Review Commission report last month, “China is a global source of illicit fentanyl and other [new psychoactive substances] because the country’s vast chemical and pharmaceutical industries are weakly regulated and poorly monitored.” In response to U.S. pressure, China has scheduled fentanyl and several other derivatives. More here.

U-47700
COMMON NAMES
U-47700
EFFECTS CLASSIFICATIONS
Opioid
CHEMICAL NAME
3,4-dichloro-N-[2-(dimethylamino)cyclohexyl]-N-methylbenzamide
DESCRIPTION
U-47700 is a short-acting synthetic opioid analgesic that first became available via online vendors in late 2014. It has only a short history of human use. U-47700 has been detected in counterfeit pharmaceutical opioids and associated with deaths.BASICS EFFECTS IMAGES HEALTH DOSE CHEMISTRY
Mar-Apr 2016 – Fake oxycodone tablets containing U-47700 are seized by law enforcement in Ohio and fake Norco tablets containing U-47700 and fentanyl appear in the Sacramento, CA area.

An 18-Year-Old Girl Died From a Synthetic Opioid She Bought Online. Here’s How Portland Police Cracked the Case.

A fatal overdose in East Portland leads detectives into the Dark Web, where lab-created opioids are bought with Bitcoin.

Courtesy of Jessica Collins

Even by Portland standards, the weather was dreary on the day Aisha Zughbieh-Collins died.

It was late morning Feb. 16 when Jessica Collins drove through a 40-degree drizzle to the pink and yellow townhouse on Southeast 84th Avenue, where Aisha, her 18-year-old daughter, lived.

Collins drove gingerly down the rutted, dead-end gravel street. It’s the kind of street that’s often lined with abandoned shopping carts.

She got out of her truck, walked into Aisha’s townhouse and climbed the stairs with a sense of dread. For the past 12 hours, Collins had been unable to reach her daughter.

Just two weeks earlier, Aisha had overdosed, her life saved when a roommate called paramedics.

As Collins entered her daughter’s bedroom, Aisha was sitting lotus-style on her bed.

“Each step closer I could tell something was really wrong,” Collins recalls.

Aisha had a syringe in her right arm, and a shoelace tourniquet tied around her biceps. She wasn’t breathing. Her skin was cold.

“I know it sounds strange,” Collins says, “but a sense of peace came over me—that she’s OK now—even though she was dead in front of me.”

Drug overdoses now kill more people than firearms or automobile crashes in Oregon, according to state figures, and are the largest cause of accidental death in the U.S. As the country’s overdose death total continues to soar, Oregon officials have responded far more effectively than officials in most states (see chart below).

Source: Centers for Disease Control
While opioid overdose deaths nationally rose 57 percent from 2010 to 2015, they actually dropped slightly in Oregon over the same period. Source: Oregon Health Authority
While opioid overdose deaths nationally rose 57 percent from 2010 to 2015, they actually dropped slightly in Oregon over the same period. Source: Oregon Health Authority

But even in Portland, which has slowed overdose deaths resulting from heroin and prescription opioids such as oxycodone, Aisha’s death is part of a new and dangerous development.

The drug that killed her was a potent “synthetic” opioid manufactured in China—a drug so new that narcotics investigators and Portland’s public health officials had never encountered it before.

“What we don’t have a lot of here yet is the synthetics,” says Dr. Paul Lewis, the Multnomah County health officer. “That could change.”

When Portland Police Bureau detectives arrived at Aisha’s townhouse, they were initially stymied. Their investigation would eventually lead them across the country and into the deepest recesses of the internet: places where the common currency is Bitcoin, and where buyers and sellers are anonymous and far removed from each other. Bitcoin is used for a lot of other purposes though, as people find it a lot easier to buy bitcoin. It just depends on the circumstances though obviously.

The trail would take them to a condo in South Carolina, and to one of the Dark Web’s most prolific synthetic opioid sellers.

“We’d never done a case like this,” says the Police Bureau detective who led the investigation. “We weren’t familiar with the substance. And we had no idea where it came from.”

Aisha Zughbieh-Collins traveled a long way in a short life that started on the Gulf Coast of Florida.

She was petite—barely 5 feet 4 inches tall, with a quick smile. She loved animals: She used to have a cat named Bebe and a Burmese python named Applejack. She liked sushi and Thai food, root beer and cream soda. She listened to Bright Eyes and Nirvana.

In November 2015, Aisha ran away from a foster-care facility in Baltimore, where her mother says she’d been assaulted. Aisha reconnected with her mother, who was also living in Maryland but who had lost custody of Aisha three years earlier.

Rather than return Aisha to foster care, the pair decided to head west to begin new lives. They left shortly before Thanksgiving. “We didn’t know where to go, but we wanted warm weather,” Collins says.

They drove west in a sunflower-colored Nissan Xterra, using throwaway phones and paying cash at cheap motels. They feared authorities might be looking for Aisha, who was 17 years old and still a ward of the state.

They arrived in Oregon in February 2016, and Collins found work as a host in a remote campground in Mount Hood National Forest.

They liked the woods, but for Aisha, there was little in the way of entertainment—nobody her age, nowhere to eat, and no WiFi. “It was hard for Aisha to be without the internet,” Collins says.

In May of that year, Aisha found a place to live on Craigslist and moved to the Brentwood-Darlington neighborhood just east of 82nd Avenue, sharing with several housemates the townhouse where she would eventually die.

Collins says her daughter had been using hard drugs in Maryland, and had started using again when Collins moved to Portland, living near Aisha.
She told her mother she was using a drug called U-47700.

U-47700, known sometimes as U4 or “pink,” was developed by the pharmaceutical company Upjohn in 1976 as an alternative to morphine but never received U.S. Food and Drug Administration approval. As a result, it was never placed on the FDA’s schedule of illicit drugs, so for decades there was no prohibition on its manufacture or distribution. It existed in a gray zone—neither approved for use nor specifically illegal.

And while Upjohn never manufactured the drug, laboratories in China—where law enforcement officials say many synthetic opioids are made—figured out how to do so.

U-47700 is also lethal—nearly eight times more potent than heroin. Records show the feds first became aware that people were using U4 to get high in October 2015, although they weren’t sure where the drug was coming from.

In the next year, they recorded 46 overdose deaths, most on the Eastern Seaboard. In November 2016, the U.S. Drug Enforcement Administration, “responding to the imminent threat to public health and safety,” made U-47700 a schedule I substance, classifying it among the most dangerous street drugs.

“I told Aisha U4 was suicide,” Collins recalls. “You can’t choose whether you live or die. It’s like Russian roulette.”

Rising Synthetic Tide: Overdose deaths from synthetic opioids rose much faster last year than overdose deaths from heroin or prescription pain pills.

Source: Centers for Disease Control
Source: Centers for Disease Control

The day Aisha died, Portland narcotics detectives arrived at her townhouse. The lead detective is a stocky cop, with salt-and-pepper hair and, considering his job, a cheery demeanor.

The detective later spoke to WW but insisted on anonymity because he works undercover. He sees a lot of dead bodies: There are about two fatal overdoses a week in Portland, most opioid-related.

But this one stood out, the detective says, not only because he’d never heard of the drug that killed Aisha, but also because she was a woman, and so young—the average overdose victim in Oregon is a man over 35.

The house where Aisha Zughbieh-Collins died. (Hilary Sanders)
The house where Aisha Zughbieh-Collins died. (Hilary Sanders)

Portland’s approach to overdose deaths changed in 2007, when Kraig Crow, a Lincoln High School graduate, fatally overdosed.

“Our policy here is different from other jurisdictions’,” the detective says. “Before, we just walked away and let the medical examiner handle it.

“After the Lincoln case,” he continues, “we started asking, ‘What can we find at the scene that can allow us to investigate further?'”

When Portland detectives respond to an overdose death now, they are looking for witnesses, phones and the packaging in which drugs are delivered.

In the Crow case, prosecutors won convictions of six defendants, including what’s called a “Len Bias conviction” for the top dealer.

That law, named after University of Maryland basketball star Len Bias, who died of a cocaine overdose in 1986 after being picked second overall in the NBA draft, became a potent tool for prosecutors because it replaced lighter sentences with a 20-year prison term for those who deal drugs leading to a death.

Federal prosecutors in Oregon are recognized as national leaders in bringing Len Bias cases.

Investigators try to determine how the fatal dose moved from the original source to the consumer, establishing a chain of custody. “Every person in the chain is potentially liable for the overdose death,” says Steve Mygrant, an assistant U.S. attorney who has prosecuted several dealers in fatal overdose cases. (Local and federal officials often cooperate on Len Bias cases.)

Aisha’s mother told detectives she thought her daughter bought U4 online, and she provided them with Aisha’s email address.

The detectives also found unusual materials in Aisha’s bedroom—distinctive packaging suggested someone had carefully disguised the U-47700 to send it through the mail.

The drug Aisha bought had been hidden in a VeriQuick brand pregnancy test kit—sold only at Dollar Tree stores—and appeared to have arrived from an unknown seller in a U.S. Postal Service shipping envelope from South Carolina.
Those were clues. But the detectives couldn’t work their way up the usual chain of delivery as they do in heroin cases.

“Our calls usually come from people complaining about a neighborhood drug house,” the detective says. “This online stuff is at a completely different level.”

The next day, the detectives asked for help from federal experts who knew how to navigate the deepest recesses of the internet.

In 2013, federal agents busted Silk Road, a vast online bazaar for drugs, child pornography, illegal weapons, stolen credit cards, valuable personal information, hacking services and even contract killers.

Silk Road operated on what’s called the Dark Web. That’s the term used to describe the vast array of websites that operate out of reach of the average web surfer.

The internet is like an iceberg: Experts say less than 5 percent of websites are visible using typical browsers such as Safari, Firefox or Chrome.

Some of what’s under the surface is benign material that is simply password-protected: legitimate financial and medical records, for instance, that are shielded for privacy reasons. But it is also used by dissidents in countries where free speech isn’t allowed—and by criminals of all kinds.

Dark Web users need a couple of things to access such sites: a specialized (and easily downloadable) browser called Tor and, if they want to remain anonymous, a tool that encrypts their communications and preserves their anonymity. Aisha used what’s called a PGP (“pretty good privacy”) key to hide her activity.

And for people who wish to buy or sell goods or services on the Dark Web, using Bitcoin or another virtual currency adds another layer of anonymity. Bitcoin, which Aisha used, allowed her to purchase drugs without creating the kind of easily traceable trail that credit or debit cards leave behind.

“But once you clear the smoke,” says George Chamberlin, chief of the FBI’s Oregon Cyber Task Force, “it’s not that different from the visible internet.”
When Silk Road disappeared because of the indictment and conviction of its creator, other Dark Web marketplaces took its place. One, called AlphaBay, offers a staggering array of illicit drugs.

Sellers hawk their wares aggressively and encourage buyers to rate their experiences just as customers do on conventional sites such as Amazon, Yelp or Trip Advisor. But instead of rating tacos or hotel rooms, buyers are rating heroin, meth or the newest kind of illicit narcotic, synthetic opioids.

“The game is changing,” the FBI’s Chamberlin says, “especially because of synthetics. They are different because of their potency and because they are trafficked on the Dark Web.”

Detectives found that Aisha had written an alphanumeric code on a pad in her bedroom. That code identified her PGP key.

They determined that Aisha’s PGP key had been used to buy drugs on AlphaBay.
The detective learned that, using her PGP, Aisha had purchased U-47700 on Feb. 11, five days before her death, from a vendor who called himself “Peter the Great”—like the Russian emperor.

A U.S. postal inspector determined the envelope found in Aisha’s bedroom had a fictitious return address but was purchased at a post office in Greenville, S.C.

In April, the Portland detective bought U4 over the Dark Web from Peter the Great. The drugs arrived, wrapped in material from Dollar Tree.

The person who purchased the shipping labels—presumably Peter the Great—used secure email addresses. The investigators then filed a subpoena for all records related to those addresses.

They turned up a name: Ted Khleborod, a resident of Greenville.

Peter the Great—who detectives now believed was Khleborod—was a prolific salesman: Figures on AlphaBay showed he’d done 9,553 transactions.

The Portland detective contacted federal officials in South Carolina. “We scared the crap out the assistant U.S. attorney back there when we told him about the substance and volume of sales,” the detective says. “This guy was sending out the equivalent of bombs.”

Ted Khleborod (Spartanburg County Sheriff’s Office)
Ted Khleborod (Spartanburg County Sheriff’s Office)

Khleborod, now 28, was born in Moldova, part of the former Soviet Union. When he was in high school, records show he spent time on bodybuilder chat boards, discussing the benefits of steroid use and posting as “Arnoldismyhero,” a tribute to former California governor and champion body builder Arnold Schwarzenegger.

He later studied at the University of South Carolina, where, according to his Facebook page, he was pre-med. He graduated in 2016.

Khleborod lived well for a college student, records show, driving a BMW—with a vanity plate that read “TEDALICUS”—and a Ducati motorcycle.

In late April, Portland detectives flew to Greenville to coordinate with local police.

For three days, they staked out Khleborod at his condo. They saw his girlfriend, Ana Barrero, leave his place twice to mail dozens of parcels, with labels matching those they’d found earlier in Aisha’s room and identical to those matching labels from the drugs that investigators bought over the Dark Web from Peter the Great.

They also obtained video of Barrero buying 71 VeriQuick pregnancy test kits at a Dollar Tree in Greenville.

On April 26, officers arrested Khleborod as he left work at an urgent care clinic. “He was a quiet guy, contemplative,” says the Portland detective. “I don’t think he used his own product, and based on his numbers, he could have made a million bucks in the past couple years.”

Khleborod, who is now in custody, faces federal charges in South Carolina. (His attorney did not respond to a request for comment.)

When officers served a search warrant on Khleborod’s condo, they wore hazmat suits to guard against the toxicity of U-47700. They hauled away 9 kilos of the drug, worth $270,000.

They also found a book, written for prospective doctors, called Kill as Few Patients as Possible.

The Portland detective says Aisha’s case revealed to him a new world of synthetic opioids and the Dark Web. He says he also realized that despite all the technically sophisticated tools dealers like Peter the Great employ, they are subject to human mistakes.

“Internet privacy—even with encryption—is not as great as you think,” the detective says. “People on the Dark Web still leave breadcrumbs we can follow.”
Jessica Collins says she’s happy police arrested Khleborod. But she remains heartbroken over her daughter’s death.

“I feel like she’s with me every day,” Collins says, “and I worry about how many other families this might happen to.”

Cam Strahm, the DEA chief for Oregon, applauds the police work that led to Khleborod’s capture. But he says after 26 years of chasing drug dealers, he’s come to understand the limits of that work.

“Addiction is a treatable disease,” he says, “and we’re facing an epidemic. We can’t arrest our way out of it.”

Aisha Collins (Courtesy of Jessica Collins)
Aisha Collins (Courtesy of Jessica Collins)

The Wages of Synthetics

The new challenge from synthetic opioids marketed over the Dark Web comes at a time when the trend in overdose deaths in Oregon is relatively positive.

Opioid deaths here have declined in recent years, while the trend in the rest of the country is still sharply upward. (The New York Times recently reported deaths jumped nearly 20 percent nationally in 2016.)

“When you look at the rest of the country, flat is good,”says Multnomah County Health Officer Dr. Paul Lewis.

There are two reasons for the good news. The first is naloxone, marketed under the brand name Narcan, a nasal spray that reverses overdoses. Under the leadership of former Multnomah County Health Officer Dr. Gary Oxman, the Portland area was a national pioneer in making naloxone widely available (“Who Wants to Save a Junkie?WW, March 13, 2013).

And Oxman’s successor, Lewis, pushed large metro-area medical systems to decrease the number of opioid pain pills prescribed to patients. That number has decreased each of the past five quarters.

Together, those two developments have caused the number of overdose deaths in Oregon to decline, a result most states would envy.

But deaths such as Aisha Zughbieh-Collins’ highlight a new danger: synthetic opioids such as fentanyl, carfentanil and U-47700 that are not prescribed by physicians but instead manufactured and sold illegally.

Lewis says there have been just two confirmed deaths in the metro area in the past 18 months in which U-47700 was the primary cause. But synthetic opioids are now the nation’s fastest-growing cause of overdose deaths. The death toll in some states is extraordinary: Last year, for instance, there were 34 deaths from synthetics in Oregon in 2015—and 949 in Massachusetts.

“The synthetic thing is new to everybody,” Lewis says. “We thought heroin was the foe, but now these synthetics come along. It’s a new chapter, and we don’t know how it ends.”

Cam Strahm of the U.S. Drug Enforcement Administration notes that synthetics such as fentanyl and carfentanil are dozens or even hundreds of times stronger than heroin.

Strahm says synthetics are also less predictable than heroin, which is now fairly standard in quality and potency. The dealers who sell synthetics often mix them in nonstandard “cocktails” and also frequently misrepresent what they are selling.

“When you are making illicit purchases from anonymous sources, you can’t depend on purity or that what you think you are buying is what you actually get,” Strahm says. “You really don’t know what you are purchasing. It’s like going on a vacation without knowing your destination.”